Open AccessWalK(S221P), a naturally occurring mutation, confers vancomycin resistance in VISA strain XN108
Author(s) -
Huagang Peng,
Qiwen Hu,
Weilong Shang,
Jizhen Yuan,
Xiaopeng Zhang,
Hui Liu,
Ying Zheng,
Zhen Hu,
Yi Yang,
Li Tan,
Shu Li,
Xiaomei Hu,
Ming Li,
Xiancai Rao
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw518
Subject(s) - vancomycin , mutant , microbiology and biotechnology , biology , mutation , gene , virulence , genetics , staphylococcus aureus , bacteria
Vancomycin-intermediate Staphylococcus aureus (VISA) strains have spread globally. We previously isolated an ST239 VISA (XN108) with a vancomycin MIC of 12 mg/L. The mechanism for XN108 resistance to vancomycin was investigated in this study.
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