Effects of isoniazid resistance on TB treatment outcomes under programmatic conditions in a high-TB and -HIV setting: a prospective multicentre study | Zendy

Tumaini Nagu | Zendy; Said Aboud | Zendy; Mecky Matee | Zendy; Markus Maeurer | Zendy; Wafaie Fawzi | Zendy; Ferdinand Mugusi | Zendy

Open Access

Effects of isoniazid resistance on TB treatment outcomes under programmatic conditions in a high-TB and -HIV setting: a prospective multicentre study

Author(s) -

Tumaini Nagu,

Said Aboud,

Mecky Matee,

Markus Maeurer,

Wafaie Fawzi,

Ferdinand Mugusi

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw503

Subject(s) - isoniazid , medicine , prospective cohort study , tuberculosis , drug resistance , pathology , microbiology and biotechnology , biology

The scale and impact of background isoniazid resistance in TB- and HIV-endemic countries requires definition to improve treatment success and guide the scale-up of isoniazid preventive therapy (IPT). We describe the effects of isoniazid resistance on TB treatment outcomes among patients with or without HIV infection in Dar es Salaam, Tanzania.

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