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Does moderate renal impairment affect clinical outcomes in complicated intra-abdominal and complicated urinary tract infections? Analysis of two randomized controlled trials with ceftolozane/tazobactam
Author(s) -
Ravina Kullar,
Florian Wagenlehner,
Myra W. Popejoy,
Jianmin Long,
Brian Yu,
Ellie J. C. Goldstein
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw486
Subject(s) - meropenem , medicine , levofloxacin , tazobactam , population , urinary system , renal function , antibiotics , imipenem , antibiotic resistance , biology , environmental health , microbiology and biotechnology
For reasons not well understood, antibacterials can yield lower cure rates in renally impaired patients. We explored this subject for the novel antibacterial ceftolozane/tazobactam.

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