The pharmacodynamics of avibactam in combination with ceftaroline or ceftazidime againstβ-lactamase-producing Enterobacteriaceae studied in anin vitromodel of infection | Zendy

Alasdair MacGowan | Zendy; Sharon Tomaselli | Zendy; Alan Noel | Zendy; Karen E. Bowker | Zendy

Open Access

The pharmacodynamics of avibactam in combination with ceftaroline or ceftazidime againstβ-lactamase-producing Enterobacteriaceae studied in anin vitromodel of infection

Author(s) -

Alasdair MacGowan,

Sharon Tomaselli,

Alan Noel,

Karen E. Bowker

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw480

Subject(s) - avibactam , enterobacter cloacae , ceftazidime , klebsiella pneumoniae , pharmacokinetics , cmax , ceftazidime/avibactam , pharmacodynamics , beta lactamase inhibitors , medicine , microbiology and biotechnology , pharmacology , chemistry , escherichia coli , antibiotics , biology , bacteria , biochemistry , genetics , pseudomonas aeruginosa , gene

Pharmacodynamics of β-lactamase inhibitors are an area of intense interest as new β-lactam/β-lactamase inhibitor combinations enter clinical development and clinical practice. Avibactam, a non-β-lactam β-lactamase inhibitor, has been combined with ceftaroline or ceftazidime but these two combinations have not been directly compared.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research