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Pharmacodynamics of β-lactamase inhibitors are an area of intense interest as new β-lactam/β-lactamase inhibitor combinations enter clinical development and clinical practice. Avibactam, a non-β-lactam β-lactamase inhibitor, has been combined with ceftaroline or ceftazidime but these two combinations have not been directly compared.

the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy

The pharmacodynamics of avibactam in combination with ceftaroline or ceftazidime against<b>β</b>-lactamase-producing Enterobacteriaceae studied in an<i>in vitro</i>model of infection

The pharmacodynamics of avibactam in combination with ceftaroline or ceftazidime againstβ-lactamase-producing Enterobacteriaceae studied in anin vitromodel of infection