In vitroactivity of gentamicin as an adjunct to penicillin against biofilm group BStreptococcus | Zendy

Corinne Ruppen | Zendy; Andrew Hemphill | Zendy; Parham Sendi | Zendy

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In vitroactivity of gentamicin as an adjunct to penicillin against biofilm group BStreptococcus

Author(s) -

Corinne Ruppen,

Andrew Hemphill,

Parham Sendi

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw447

Subject(s) - gentamicin , penicillin , microbiology and biotechnology , biofilm , streptococcus , minimum inhibitory concentration , bacteria , antibiotics , in vitro , medicine , chemistry , biology , biochemistry , genetics

Group B Streptococcus (GBS) increasingly causes invasive disease in non-pregnant adults, particularly in elderly persons and those with underlying diseases. Combination therapy with penicillin plus gentamicin has been suggested for periprosthetic joint infection. The postulated synergism of this combination is based on experiments with planktonic bacteria. We aimed to assess the efficacy of this combination against sessile bacteria.

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