In vitro activity of daptomycin combined with dalbavancin and linezolid, and dalbavancin with linezolid against MRSA strains | Zendy

Gülseren Aktaş | Zendy; Şengül Derbentli | Zendy

Open Access

In vitro activity of daptomycin combined with dalbavancin and linezolid, and dalbavancin with linezolid against MRSA strains

Author(s) -

Gülseren Aktaş,

Şengül Derbentli

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw416

Subject(s) - daptomycin , dalbavancin , linezolid , antibiotics , microbiology and biotechnology , staphylococcus aureus , antimicrobial , pharmacology , vancomycin , medicine , biology , bacteria , genetics

Combination therapies have a distinct advantage over monotherapies in terms of their broad spectrum, synergistic effect and prevention of the emergence of drug resistance. In the present study, the in vitro antibacterial activity of daptomycin combinations with linezolid and dalbavancin, and dalbavancin with linezolid were evaluated against 30 clinical MRSA strains.

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