Effect of diurnal variation,CYP2B6genotype and age on the pharmacokinetics of nevirapine in African children
Author(s) -
Andrzej Bienczak,
Adrian Cook,
Lubbe Wiesner,
Veronica Mulenga,
Cissy Kityo,
Addy Kekitiinwa,
A. Sarah Walker,
Andrew Owen,
Diana M. Gibb,
David M. Burger,
Helen McIlleron,
Paolo Denti
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw388
Subject(s) - nevirapine , pharmacokinetics , diurnal temperature variation , cyp2b6 , genotype , medicine , human immunodeficiency virus (hiv) , pharmacology , biology , virology , genetics , geography , antiretroviral therapy , meteorology , viral load , cytochrome p450 , metabolism , cyp3a4 , gene
To characterize the effects of CYP2B6 polymorphisms, diurnal variation and demographic factors on nevirapine pharmacokinetics in African children.
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