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Low biological cost of carbapenemase-encoding plasmids following transfer from Klebsiella pneumoniae to Escherichia coli
Author(s) -
Maria Chiara Di Luca,
Vidar Sørum,
И В Старикова,
Julia Kloos,
Nils F. Hülter,
Umaer Naseer,
Pål J. Johnsen,
Ørjan Samuelsen
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw350
Subject(s) - plasmid , klebsiella pneumoniae , biology , escherichia coli , microbiology and biotechnology , enterobacteriaceae , transformation (genetics) , genetics , dna , gene
The objective of this study was to determine the biological cost, stability and sequence of two carbapenemase-encoding plasmids containing bla KPC-2 (pG12-KPC-2) and bla VIM-1 (pG06-VIM-1) isolated from Klebsiella pneumoniae when newly acquired by uropathogenic Escherichia coli clinical isolates of different genetic backgrounds.

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