Low biological cost of carbapenemase-encoding plasmids following transfer from Klebsiella pneumoniae to Escherichia coli
Author(s) -
Maria Chiara Di Luca,
Vidar Sørum,
И В Старикова,
Julia Kloos,
Nils F. Hülter,
Umaer Naseer,
Pål J. Johnsen,
Ørjan Samuelsen
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw350
Subject(s) - plasmid , klebsiella pneumoniae , biology , escherichia coli , microbiology and biotechnology , enterobacteriaceae , transformation (genetics) , genetics , dna , gene
The objective of this study was to determine the biological cost, stability and sequence of two carbapenemase-encoding plasmids containing bla KPC-2 (pG12-KPC-2) and bla VIM-1 (pG06-VIM-1) isolated from Klebsiella pneumoniae when newly acquired by uropathogenic Escherichia coli clinical isolates of different genetic backgrounds.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom