Structural equation modelling of viral tropism reveals its impact on achieving viral suppression within 6 months in treatment-naive HIV-1-infected patients after combination antiretroviral therapy
Author(s) -
Carlo Mengoli,
Samantha Andreis,
Renzo Scaggiante,
Mario Cruciani,
Oliviero Bosco,
Roberto Ferretto,
Davide Leoni,
Gaetano Maffongelli,
Monica Basso,
Carlo Torti,
Loredana Sarmati,
Massimo Andreoni,
Giorgio Palù,
Saverio Giuseppe Parisi
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw348
Subject(s) - tropism , cart , viral load , virology , virus , context (archaeology) , tissue tropism , immunology , human immunodeficiency virus (hiv) , cohort , biology , medicine , mechanical engineering , paleontology , engineering
To evaluate the role of pre-treatment co-receptor tropism of plasma HIV on the achievement of viral suppression (plasma HIV RNA 1.69 log 10 copies/mL) at the sixth month of combination antiretroviral therapy (cART) in a cohort of naive patients using, for the first time in this context, a path analysis (PA) approach.
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