Assessment of antivirulence activity of several d-amino acids againstAcinetobacter baumanniiandPseudomonas aeruginosa | Zendy

Carlos Rumbo | Zendy; Juán A. Vallejo | Zendy; María P. Cabral | Zendy; Marta Martínez-Guitián | Zendy; Astrid Pérez | Zendy; Alejandro Beceiro | Zendy; Germán Bou | Zendy

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Assessment of antivirulence activity of several d-amino acids againstAcinetobacter baumanniiandPseudomonas aeruginosa

Author(s) -

Carlos Rumbo,

Juán A. Vallejo,

María P. Cabral,

Marta Martínez-Guitián,

Astrid Pérez,

Alejandro Beceiro,

Germán Bou

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw342

Subject(s) - pseudomonas aeruginosa , acinetobacter baumannii , biofilm , microbiology and biotechnology , amino acid , virulence , bacteria , biology , in vivo , antibiotics , in vitro , chemistry , biochemistry , gene , genetics

Biofilm formation and bacterial adherence are important requirements for persistence, multidrug resistance and infection. The d-amino acids play a role as modulators of bacterial growth and persistence, though their ability to inhibit biofilms is much debated. In this study, we analysed the effects of 18 different d-amino acids on the pathogens Acinetobacter baumannii and Pseudomonas aeruginosa.

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