Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis : a retrospective observational cohort study of the Mycoses Study Group (MSG-12): Table 1. | Zendy

Kathleen Chiotos | Zendy; Neika Vendetti | Zendy; Theoklis E. Zaoutis | Zendy; John W. Baddley | Zendy; Luis OstroskyZeichner | Zendy; Peter G. Pappas | Zendy; Brian T. Fisher | Zendy

Open Access

Comparative effectiveness of echinocandins versus fluconazole therapy for the treatment of adult candidaemia due to Candida parapsilosis : a retrospective observational cohort study of the Mycoses Study Group (MSG-12): Table 1.

Author(s) -

Kathleen Chiotos,

Neika Vendetti,

Theoklis E. Zaoutis,

John W. Baddley,

Luis OstroskyZeichner,

Peter G. Pappas,

Brian T. Fisher

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw305

Subject(s) - echinocandin , anidulafungin , fluconazole , echinocandins , candida parapsilosis , medicine , caspofungin , fungemia , propensity score matching , retrospective cohort study , mycosis , surgery , antifungal , dermatology

A polymorphism in the gene encoding β-1,3-glucan synthase, the target of the echinocandin class of antifungals, results in increased in vitro MICs of the echinocandins. This has resulted in controversy surrounding use of the echinocandins for treatment of Candida parapsilosis candidaemia. We aimed to compare 30 day mortality in adults with C. parapsilosis candidaemia treated with echinocandins versus fluconazole.

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