Population pharmacokinetics and pharmacodynamics of teicoplanin in neonates: making better use of C-reactive protein to deliver individualized therapy | Zendy

V. Ramos-Martín | Zendy; Michael Neely | Zendy; Patricia M. McGowan | Zendy; Sarah Siner | Zendy; K. Padmore | Zendy; Matthew Peak | Zendy; MW Beresford | Zendy; M. Turner | Zendy; Stéphane Paulus | Zendy; William Hope | Zendy

Open Access

Population pharmacokinetics and pharmacodynamics of teicoplanin in neonates: making better use of C-reactive protein to deliver individualized therapy

Author(s) -

V. Ramos-Martín,

Michael Neely,

Patricia M. McGowan,

Sarah Siner,

K. Padmore,

Matthew Peak,

MW Beresford,

M. Turner,

Stéphane Paulus,

William Hope

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw295

Subject(s) - cmin , teicoplanin , medicine , pharmacodynamics , pharmacokinetics , population , regimen , nonmem , pharmacology , cmax , vancomycin , biology , environmental health , bacteria , genetics , staphylococcus aureus

There is uncertainty about the optimal teicoplanin regimens for neonates. The study aim was to determine the population pharmacokinetics (PK) of teicoplanin in neonates, evaluate currently recommended regimens and explore the exposure-effect relationships.

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