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High efficacy of first-line ART in a West African cohort, assessed by dried blood spot virological and pharmacological measurements
Author(s) -
Pierre de Truchis,
Minh Patrick Lê,
Mamane Daou,
Boubacar Madougou,
Yacouba Nouhou,
Sahada Moussa Saley,
Achirou Sani,
Eric Adéhossi,
É. Rouveix,
Saïdou Mamadou,
Gilles Peytavin,
Constance Delaugerre
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw286
Subject(s) - dried blood spot , efavirenz , nevirapine , etravirine , emtricitabine , viral load , medicine , rilpivirine , drug resistance , lamivudine , abacavir , virology , human immunodeficiency virus (hiv) , biology , antiretroviral therapy , virus , microbiology and biotechnology , hepatitis b virus , genetics
The objectives of this study were to determine the rate of viral success in HIV-infected patients on first-line ART by the assessment of dried blood spot (DBS) viral load (VL) and to assess the performance of DBS sampling for VL measurement, genotypic resistance and antiretroviral concentration determinations.

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