Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4Escherichia coliclonal complex | Zendy

Nicolas Dufour | Zendy; Olivier Clermont | Zendy; Béatrice La Combe | Zendy; Jonathan Messika | Zendy; Sara Dion | Zendy; Varun Khanna | Zendy; Erick Denamur | Zendy; Jean-Damien Ricard | Zendy; Laurent Debarbieux | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4Escherichia coliclonal complex

Author(s) -

Nicolas Dufour,

Olivier Clermont,

Béatrice La Combe,

Jonathan Messika,

Sara Dion,

Varun Khanna,

Erick Denamur,

Jean-Damien Ricard,

Laurent Debarbieux

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw253

Subject(s) - bacteriophage , microbiology and biotechnology , escherichia coli , phage therapy , biology , virology , antibiotics , antibiotic resistance , population , virulence , bacteria , genetics , gene , medicine , environmental health

Amongst the highly diverse Escherichia coli population, the ST131-O25b:H4 clonal complex is particularly worrisome as it is associated with a high level of antibiotic resistance. The lack of new antibiotics, the worldwide continuous increase of infections caused by MDR bacteria and the need for narrow-spectrum antimicrobial agents have revived interest in phage therapy. In this article, we describe a virulent bacteriophage, LM33_P1, which specifically infects O25b strains, and provide data related to its therapeutic potential.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research