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Clostridium difficile infection (CDI) is a major public health concern. Treatment with commonly prescribed antibiotics is associated with high rates of recurrence after initial cure. Here, we present the efficacy and safety of surotomycin, an orally administered, minimally absorbed, selective bactericidal cyclic lipopeptide, compared with vancomycin, in patients with CDI.

the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy

Surotomycin versus vancomycin for<i>Clostridium difficile</i>infection: Phase 2, randomized, controlled, double-blind, non-inferiority, multicentre trial

Surotomycin versus vancomycin forClostridium difficileinfection: Phase 2, randomized, controlled, double-blind, non-inferiority, multicentre trial