Evaluation of different pretreatment protocols to detect accurately clinical carbapenemase-producing Enterobacteriaceae by MALDI-TOF | Zendy

Carmine G. Monteferrante | Zendy; Sadaf Sultan | Zendy; Marian T. ten Kate | Zendy; Lennard J. M. Dekker | Zendy; Katrin Sparbier | Zendy; Markus Peer | Zendy; Markus Kostzrewa | Zendy; Theo M. Luider | Zendy; Wil H. F. Goessens | Zendy; Peter C. Burgers | Zendy

Open Access

Evaluation of different pretreatment protocols to detect accurately clinical carbapenemase-producing Enterobacteriaceae by MALDI-TOF

Author(s) -

Carmine G. Monteferrante,

Sadaf Sultan,

Marian T. ten Kate,

Lennard J. M. Dekker,

Katrin Sparbier,

Markus Peer,

Markus Kostzrewa,

Theo M. Luider,

Wil H. F. Goessens,

Peter C. Burgers

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw208

Subject(s) - ertapenem , imipenem , carbapenem , microbiology and biotechnology , enterobacteriaceae , antibiotics , carbapenem resistant enterobacteriaceae , biology , antibiotic resistance , escherichia coli , biochemistry , gene

Carbapenemase-resistant bacteria are increasingly spreading worldwide causing public concern due to their ability to elude antimicrobial treatment. Early identification of these bacteria is therefore of high importance. Here, we describe the development of a simple and robust protocol for the detection of carbapenemase activity in clinical isolates of Enterobacteriaceae, suitable for routine and clinical applications.

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