Combination ofCandidabiomarkers in patients receiving empirical antifungal therapy in a Spanish tertiary hospital: a potential role in reducing the duration of treatment | Zendy

M. Carmen Martínez-Jiménez | Zendy; Patricia Muñóz | Zendy; Maricela Valerio | Zendy; Antonio Vena | Zendy; Jesús Guinea | Zendy; Emilio Bouza | Zendy

Open Access

Combination ofCandidabiomarkers in patients receiving empirical antifungal therapy in a Spanish tertiary hospital: a potential role in reducing the duration of treatment

Author(s) -

M. Carmen Martínez-Jiménez,

Patricia Muñóz,

Maricela Valerio,

Antonio Vena,

Jesús Guinea,

Emilio Bouza

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw193

Subject(s) - antifungal , medicine , tertiary care , candida infections , fungemia , intensive care medicine , dermatology

Methods: This was a prospective observational study including adults starting empirical antifungal treatment for suspected IC, at Gregorio Marañón Hospital, Madrid (Spain). Patients were stratified according to admission department (ICU or other wards) and final diagnosis (no IC or proven or probable IC). Type of candidiasis (candidaemia or deep-seated candidiasis) was also considered. The Candida albicans germ tube antibody (CAGTA) test and the b-D-glucan (BDG) test were performed on serum samples collected by venepuncture on days 0, 3 and 5 after starting empirical antifungal therapy.

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