Open AccessGlutathione-S-transferase FosA6 ofKlebsiella pneumoniaeorigin conferring fosfomycin resistance in ESBL-producingEscherichia coli
Author(s) -
Qinglan Guo,
Adam D. Tomich,
Christi L. McElheny,
Vaughn S. Cooper,
Nicole Stoesser,
Minggui Wang,
Nicolas SluisCremer,
Yohei Doi
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw177
Subject(s) - fosfomycin , klebsiella pneumoniae , escherichia coli , plasmid , microbiology and biotechnology , biology , genetics , gene , antibiotics
The objectives of this study were to elucidate the genetic context of a novel plasmid-mediated fosA variant, fosA6, conferring fosfomycin resistance and to characterize the kinetic properties of FosA6.
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