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In vitroandin vivostudies of a potent capsid-binding inhibitor of enterovirus 71
Author(s) -
JinYuan Ho,
JyhHaur Chern,
Chung-Fan Hsieh,
Szu-Ting Liu,
Chien-Jou Liu,
Ya-Sian Wang,
Ta-Wei Kuo,
Sheng-Ju Hsu,
TengKuang Yeh,
ShinRu Shih,
PeiWen Hsieh,
ChengHsun Chiu,
JimTong Horng
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw101
Subject(s) - in vivo , capsid , virus , enterovirus 71 , virology , coxsackievirus , in vitro , chemistry , enterovirus , biology , biochemistry , microbiology and biotechnology
Enterovirus 71 (EV-A71) is an important pathogen that can cause severe neurological symptoms and even death. Our aim was to identify potent anti-EV-A71 compounds and study their underlying mechanisms and in vivo activity.

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