Ciprofloxacin and ceftriaxone alter cytokine responses, but not Toll-like receptors, toSalmonellainfectionin vitro | Zendy

Olachi Anuforom | Zendy; Graham R. Wallace | Zendy; Michelle M. C. Buckner | Zendy; Laura J. V. Piddock | Zendy

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Ciprofloxacin and ceftriaxone alter cytokine responses, but not Toll-like receptors, toSalmonellainfectionin vitro

Author(s) -

Olachi Anuforom,

Graham R. Wallace,

Michelle M. C. Buckner,

Laura J. V. Piddock

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw092

Subject(s) - salmonella , ciprofloxacin , ceftriaxone , microbiology and biotechnology , antibiotics , cytokine , salmonella infection , biology , immune system , macrophage , receptor , in vitro , immunology , bacteria , biochemistry , genetics

Antibiotics that enhance host natural defences to infection offer an alternative approach to treating infections. However, mechanisms underlying such processes are poorly understood. The aim of this study was to investigate the effects of clinically relevant concentrations of two antibiotics on bacterial interactions with murine macrophages.

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