Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: potential contribution to HIV-1 sanctuary site | Zendy

Yiying Billy Huang | Zendy; Md. Tozammel Hoque | Zendy; MohammadAli Jenabian | Zendy; Kishanda Vyboh | Zendy; Sana-Kay Whyte | Zendy; Nancy L. Sheehan | Zendy; P. Brassard | Zendy; Maud Bélanger | Zendy; Nicolas Chomont | Zendy; Courtney V. Fletcher | Zendy; JeanPierre Routy | Zendy; Reina Bendayan | Zendy

Open Access

Antiretroviral drug transporters and metabolic enzymes in human testicular tissue: potential contribution to HIV-1 sanctuary site

Author(s) -

Yiying Billy Huang,

Md. Tozammel Hoque,

MohammadAli Jenabian,

Kishanda Vyboh,

Sana-Kay Whyte,

Nancy L. Sheehan,

P. Brassard,

Maud Bélanger,

Nicolas Chomont,

Courtney V. Fletcher,

JeanPierre Routy,

Reina Bendayan

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw046

Subject(s) - human immunodeficiency virus (hiv) , transporter , antiretroviral drug , drug , biology , enzyme , virology , pharmacology , antiretroviral therapy , biochemistry , viral load , gene

The testes are a potential viral sanctuary site for HIV-1 infection. Our study aims to provide insight into the expression and localization of key drug transporters and metabolic enzymes relevant to ART in this tissue compartment.

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