Trough concentration of voriconazole and its relationship with efficacy and safety: a systematic review and meta-analysis | Zendy

Haiying Jin | Zendy; Tiansheng Wang | Zendy; Bonnie Falcione | Zendy; Keith M. Olsen | Zendy; Ken Chen | Zendy; Huilin Tang | Zendy; John P K Hui | Zendy; Suodi Zhai | Zendy

Open Access

Trough concentration of voriconazole and its relationship with efficacy and safety: a systematic review and meta-analysis

Author(s) -

Haiying Jin,

Tiansheng Wang,

Bonnie Falcione,

Keith M. Olsen,

Ken Chen,

Huilin Tang,

John P K Hui,

Suodi Zhai

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw045

Subject(s) - voriconazole , medicine , trough concentration , cochrane library , adverse effect , incidence (geometry) , meta analysis , gastroenterology , pharmacology , pharmacokinetics , physics , optics , antifungal , dermatology

The optimum trough concentration of voriconazole for clinical response and safety is controversial. The objective of this review was to determine the optimum trough concentration of voriconazole and evaluate its relationship with efficacy and safety.

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