Resistance and cross-resistance profile of the diaryltriazine NNRTI and candidate microbicide UAMC01398
Author(s) -
Kevin K. Ariën,
Muthusamy Venkatraj,
Johan Míchiels,
Jurgen Joossens,
Katleen Vereecken,
Pieter Van der Veken,
Jan Heeres,
Hans De Winter,
Leo Heyndrickx,
Koen Augustyns,
Guido Vanham
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkv501
Subject(s) - microbicide , rilpivirine , cross resistance , virology , resistance mutation , biology , drug resistance , reverse transcriptase , reverse transcriptase inhibitor , human immunodeficiency virus (hiv) , genetics , viral load , antiretroviral therapy , gene , polymerase chain reaction
The resistance development, cross-resistance to other NNRTIs and the impact of resistance on viral replicative fitness were studied for the new and potent NNRTI UAMC01398.
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