Improved darunavir genotypic mutation score predicting treatment response for patients infected with HIV-1 subtype B and non-subtype B receiving a salvage regimen | Zendy

Andrea De Luca | Zendy; Philippe Flandre | Zendy; David Dunn | Zendy; Maurizio Zazzi | Zendy; Annemarie Wensing | Zendy; Maria Mercedes Santoro | Zendy; Huldrych F. Günthard | Zendy; Linda Wittkop | Zendy; Theodoros Kordossis | Zendy; Féderico García | Zendy; Antonella Castagna | Zendy; Alessandro CozziLepri | Zendy; Duncan Churchill | Zendy; Christoph Stephan | Zendy; Norbert H. Brockmeyer | Zendy; Arkaitz Imaz | Zendy; Cristina Mussini | Zendy; Niels Obel | Zendy; Carlo Federico Perno | Zendy; Bernardino Roca | Zendy; Peter Reiss | Zendy; Eugen Schülter | Zendy; Carlo Torti | Zendy; Ard van Sighem | Zendy; Robert Zangerle | Zendy; Diane Descamps | Zendy

Open Access

Improved darunavir genotypic mutation score predicting treatment response for patients infected with HIV-1 subtype B and non-subtype B receiving a salvage regimen

Author(s) -

Andrea De Luca,

Philippe Flandre,

David Dunn,

Maurizio Zazzi,

Annemarie Wensing,

Maria Mercedes Santoro,

Huldrych F. Günthard,

Linda Wittkop,

Theodoros Kordossis,

Féderico García,

Antonella Castagna,

Alessandro CozziLepri,

Duncan Churchill,

Christoph Stephan,

Norbert H. Brockmeyer,

Arkaitz Imaz,

Cristina Mussini,

Niels Obel,

Carlo Federico Perno,

Bernardino Roca,

Peter Reiss,

Eugen Schülter,

Carlo Torti,

Ard van Sighem,

Robert Zangerle,

Diane Descamps

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv465

Subject(s) - darunavir , enfuvirtide , raltegravir , receiver operating characteristic , maraviroc , regimen , medicine , oncology , virology , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy , immunology , gp41 , antigen , epitope

The objective of this study was to improve the prediction of the impact of HIV-1 protease mutations in different viral subtypes on virological response to darunavir.

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