Simultaneous assessment of the pharmacokinetics of a pleuromutilin, lefamulin, in plasma, soft tissues and pulmonary epithelial lining fluid | Zendy

Markus Zeitlinger | Zendy; Richard Schwameis | Zendy; Angela Burian | Zendy; Bernhard Burian | Zendy; Peter Matzneller | Zendy; Markus Müller | Zendy; W. W. Wicha | Zendy; Dirk B Strickmann | Zendy; William Prince | Zendy

Open Access

Simultaneous assessment of the pharmacokinetics of a pleuromutilin, lefamulin, in plasma, soft tissues and pulmonary epithelial lining fluid

Author(s) -

Markus Zeitlinger,

Richard Schwameis,

Angela Burian,

Bernhard Burian,

Peter Matzneller,

Markus Müller,

W. W. Wicha,

Dirk B Strickmann,

William Prince

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv442

Subject(s) - pharmacokinetics , adipose tissue , microdialysis , subcutaneous tissue , medicine , pharmacology , antibiotics , soft tissue , bronchoalveolar lavage , respiratory tract , drug , pharmacodynamics , pathology , lung , respiratory system , biology , microbiology and biotechnology , central nervous system

Lefamulin is a pleuromutilin antibiotic under evaluation for the treatment of bacterial infections, including respiratory tract infections. Currently, there are no high-quality pharmacokinetic data on drug tissue concentrations of lefamulin available.

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