What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients? | Zendy

Abdulaziz S. Alobaid | Zendy; Alexander Brinkmann | Zendy; Otto Frey | Zendy; Anka C. Roehr | Zendy; Sònia Luque | Zendy; Santiago Grau | Zendy; Gloria Wong | Zendy; Mohd H. AbdulAziz | Zendy; Michael S. Roberts | Zendy; Jeffrey Lipman | Zendy; Jason A. Roberts | Zendy

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What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?

Author(s) -

Abdulaziz S. Alobaid,

Alexander Brinkmann,

Otto Frey,

Anka C. Roehr,

Sònia Luque,

Santiago Grau,

Gloria Wong,

Mohd H. AbdulAziz,

Michael S. Roberts,

Jeffrey Lipman,

Jason A. Roberts

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv412

Subject(s) - meropenem , critically ill , medicine , piperacillin , piperacillin/tazobactam , trough (economics) , intensive care medicine , critical illness , antibiotics , microbiology and biotechnology , biology , bacteria , genetics , antibiotic resistance , pseudomonas aeruginosa , macroeconomics , economics

The objectives of this study were to determine the effects of obesity on unbound trough concentrations and on the achievement of pharmacokinetic (PK)/pharmacodynamic (PD) targets of piperacillin and meropenem in critically ill patients.

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