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The objective of this study was to investigate macrolide-resistant Streptococcus agalactiae isolates harbouring erm(TR), an erm(A) gene subclass, with emphasis on their erm(TR)-carrying genetic elements. Four erm(TR)-carrying elements have been described to date: three closely related (ICE10750-RD.2, Tn1806 and ICESp1108) in Streptococcus pyogenes, Streptococcus pneumoniae and S. pyogenes, respectively; and one completely different (IMESp2907, embedded in ICESp2906 to form ICESp2905) in S. pyogenes.

the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy

Macrolide resistance geneerm(TR) anderm(TR)-carrying genetic elements inStreptococcus agalactiae: characterization of ICESagTR7, a new composite element containing IMESp2907