In vitroantimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria | Zendy

Akinobu Ito | Zendy; Naoki Kohira | Zendy; Samuel K. Bouchillon | Zendy; Joshua West | Zendy; Stephen Rittenhouse | Zendy; Hélio S. Sader | Zendy; Paul R. Rhomberg | Zendy; Ronald N. Jones | Zendy; Hidenori Yoshizawa | Zendy; Rio Nakamura | Zendy; Masakatsu Tsuji | Zendy; Yoshinori Yamano | Zendy

Open Access

In vitroantimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria

Author(s) -

Akinobu Ito,

Naoki Kohira,

Samuel K. Bouchillon,

Joshua West,

Stephen Rittenhouse,

Hélio S. Sader,

Paul R. Rhomberg,

Ronald N. Jones,

Hidenori Yoshizawa,

Rio Nakamura,

Masakatsu Tsuji,

Yoshinori Yamano

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv402

Subject(s) - acinetobacter baumannii , microbiology and biotechnology , cefepime , meropenem , stenotrophomonas maltophilia , pseudomonas aeruginosa , piperacillin , cephalosporin , biology , ceftazidime , tazobactam , bacteria , antibiotics , imipenem , antibiotic resistance , genetics

S-649266 is a parenteral siderophore cephalosporin antibiotic with a catechol moiety on its side chain. The in vitro antimicrobial activity of S-649266 against non-fermenting Gram-negative bacteria was evaluated and compared with the activities of meropenem, levofloxacin, cefepime, ceftazidime and piperacillin/tazobactam.

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