Drug resistance and tropism as markers of the dynamics of HIV-1 DNA quasispecies in blood cells of heavily pretreated patients who achieved sustained virological suppression
Author(s) -
Pierre Gantner,
Laurence MorandJoubert,
Charlotte Sueur,
François Raffi,
Catherine Fagard,
Caroline LascouxCombe,
Dominique Salmon,
Corinne Amiel,
Sidonie Lambert-Niclot,
Djeneba Fofana,
JeanPaul Viard,
Samira FafiKremer,
Christine Rouzioux,
Véronique Avettand-Fènoël,
Jade Ghosn
Publication year - 2015
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkv395
Subject(s) - viral quasispecies , virology , tropism , drug , drug resistance , human immunodeficiency virus (hiv) , dna , hiv drug resistance , medicine , biology , virus , viral load , microbiology and biotechnology , pharmacology , antiretroviral therapy , genetics , hepatitis c virus
The objective of this study was to address the dynamics of archived resistant quasispecies in cell-associated HIV-1 DNA over time in heavily ART-experienced patients with currently suppressed plasma HIV-1 RNA.
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