Toxicity to sensory neurons and Schwann cells in experimental linezolid-induced peripheral neuropathy | Zendy

Ilja Bobylev | Zendy; Helina Maru | Zendy; Abhijeet Joshi | Zendy; Helmar C. Lehmann | Zendy

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Toxicity to sensory neurons and Schwann cells in experimental linezolid-induced peripheral neuropathy

Author(s) -

Ilja Bobylev,

Helina Maru,

Abhijeet Joshi,

Helmar C. Lehmann

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv386

Subject(s) - linezolid , peripheral neuropathy , in vivo , sciatic nerve , schwann cell , pharmacology , medicine , sensory system , pathology , anesthesia , biology , neuroscience , endocrinology , bacteria , genetics , diabetes mellitus , staphylococcus aureus , microbiology and biotechnology , vancomycin

Peripheral neuropathy is a common side effect of prolonged treatment with linezolid. This study aimed to explore injurious effects of linezolid on cells of the peripheral nervous system and to establish in vivo and in vitro models of linezolid-induced peripheral neuropathy.

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