Open AccessEffects of fluconazole on the metabolomic profile ofCandida albicans
Author(s) -
Aspasia Katragkou,
Elizabeth Alexander,
Hyungjin Eoh,
Saki Raheem,
Emmanuel Roilides,
Thomas J. Walsh
Publication year - 2015
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkv381
Subject(s) - metabolic pathway , candida albicans , metabolomics , corpus albicans , metabolome , metabolism , fluconazole , biochemistry , biology , glutamine , amino acid , chemistry , metabolite , microbiology and biotechnology , bioinformatics , antifungal
Little is known about the effects of fluconazole on the metabolism of Candida albicans. We performed LC/MS-based metabolomic profiling of the response of C. albicans cells to increasing doses of fluconazole.
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