Efficacy of ertapenem in severe hidradenitis suppurativa: a pilot study in a cohort of 30 consecutive patients | Zendy

Olivier JoinLambert | Zendy; Hélène Coignard-Biehler | Zendy; Jean-Philippe Jaı̈s | Zendy; M. Delage | Zendy; Hélène GuetRevillet | Zendy; S. Poirée | Zendy; Sabine Duchatelet | Zendy; Vincent Jullien | Zendy; Alain Hovnanian | Zendy; Olivier Lortholary | Zendy; Xavier Nassif | Zendy; Aude Nassif | Zendy

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Efficacy of ertapenem in severe hidradenitis suppurativa: a pilot study in a cohort of 30 consecutive patients

Author(s) -

Olivier JoinLambert,

Hélène Coignard-Biehler,

Jean-Philippe Jaı̈s,

M. Delage,

Hélène GuetRevillet,

S. Poirée,

Sabine Duchatelet,

Vincent Jullien,

Alain Hovnanian,

Olivier Lortholary,

Xavier Nassif,

Aude Nassif

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv361

Subject(s) - ertapenem , medicine , hidradenitis suppurativa , surgery , cohort , adverse effect , antibiotics , disease , antibiotic resistance , meropenem , microbiology and biotechnology , biology

Hidradenitis suppurativa (HS) is an inflammatory skin disease typically localized in the axillae and inguinal and perineal areas. In the absence of standardized medical treatment, severe HS patients present chronic suppurative lesions with polymicrobial anaerobic abscesses. Wide surgery is the cornerstone treatment of severe HS, but surgical indications are limited by the extent of lesions. Intravenous broad-spectrum antibiotics may help control HS, but their efficacy is not documented. This study was designed to assess the efficacy of a 6 week course of ertapenem (1 g daily) and of antibiotic consolidation treatments for 6 months (M6) in severe HS.

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