Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes | Zendy

Hervé Nicoloff | Zendy; Dan I. Andersson | Zendy

Open Access

Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes

Author(s) -

Hervé Nicoloff,

Dan I. Andersson

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv312

Subject(s) - antibiotics , microbiology and biotechnology , bacteria , antibiotic resistance , population , biology , antimicrobial , ampicillin , fosfomycin , mecillinam , biochemistry , escherichia coli , enterobacteriaceae , medicine , gene , genetics , environmental health

Indirect resistance (IR), the ability of an antibiotic-resistant population of bacteria to protect a susceptible population, has been previously observed for β-lactamase-producing bacteria and associated with antimicrobial treatment failures. Here, we determined whether other resistance determinants could cause IR in the presence of five other classes of antibiotics.

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