Direct real-time PCR-based detection ofNeisseria gonorrhoeae23S rRNA mutations associated with azithromycin resistance | Zendy

Ella Trembizki | Zendy; Cameron Buckley | Zendy; Basil Donovan | Zendy; Marcus Y. Chen | Zendy; Rebecca Guy | Zendy; John Kaldor | Zendy; Monica M Lahra | Zendy; David G. Regan | Zendy; Helen Smith | Zendy; James Ward | Zendy; David M. Whiley | Zendy

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Direct real-time PCR-based detection ofNeisseria gonorrhoeae23S rRNA mutations associated with azithromycin resistance

Author(s) -

Ella Trembizki,

Cameron Buckley,

Basil Donovan,

Marcus Y. Chen,

Rebecca Guy,

John Kaldor,

Monica M Lahra,

David G. Regan,

Helen Smith,

James Ward,

David M. Whiley

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv274

Subject(s) - neisseria gonorrhoeae , azithromycin , 23s ribosomal rna , microbiology and biotechnology , ceftriaxone , biology , gonorrhea , virology , genetics , antibiotics , gene , rna , human immunodeficiency virus (hiv) , ribosome

Surveillance for Neisseria gonorrhoeae azithromycin resistance is of growing importance given increasing use of ceftriaxone and azithromycin dual therapy for gonorrhoea treatment. In this study, we developed two real-time PCR methods for direct detection of two key N. gonorrhoeae 23S rRNA mutations associated with azithromycin resistance.

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