HIV-1 RNA and HIV-1 DNA persistence during suppressive ART with PI-based or nevirapine-based regimens | Zendy

Maja Kiselinova | Zendy; Anna María Geretti | Zendy; Eva Malatinková | Zendy; Karen Vervisch | Zendy; Apostolos Beloukas | Zendy; Peter Messiaen | Zendy; Pawel Bonczkowski | Zendy; Wim Trypsteen | Zendy; Steven Callens | Zendy; Chris Verhofstede | Zendy; Ward De Spiegelaere | Zendy; Linos Vandekerckhove | Zendy

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HIV-1 RNA and HIV-1 DNA persistence during suppressive ART with PI-based or nevirapine-based regimens

Author(s) -

Maja Kiselinova,

Anna María Geretti,

Eva Malatinková,

Karen Vervisch,

Apostolos Beloukas,

Peter Messiaen,

Pawel Bonczkowski,

Wim Trypsteen,

Steven Callens,

Chris Verhofstede,

Ward De Spiegelaere,

Linos Vandekerckhove

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv250

Subject(s) - nevirapine , rna , virology , viral load , peripheral blood mononuclear cell , dna , persistence (discontinuity) , biology , viral replication , human immunodeficiency virus (hiv) , digital polymerase chain reaction , medicine , virus , microbiology and biotechnology , antiretroviral therapy , gene , polymerase chain reaction , in vitro , genetics , geotechnical engineering , engineering

Whether ART regimens differ in their propensity to allow persistent HIV-1 detection remains unclear. To investigate this, we performed a cross-sectional study to characterize HIV-1 persistence in peripheral blood during suppressive therapy with NRTIs plus a PI or nevirapine.

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