Open AccessQuantifying the impact of drug combination regimens on TB treatment efficacy and multidrug resistance probability
Author(s) -
YiJun Lin,
ChungMin Liao
Publication year - 2015
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkv247
Subject(s) - medicine , multiple drug resistance , drug , drug resistance , regimen , efficacy , tuberculosis , pharmacology , intensive care medicine , biology , microbiology and biotechnology , pathology
TB patients' non-adherence to the multidrug treatment regimen is thought to be the main cause of the emergence of drug resistance. The purpose of this study was to quantify the impacts of two-drug combination regimens and non-adherence to these regimens on treatment efficacy and drug resistance probability.
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