Multiple pathways of cross-resistance to glycopeptides and daptomycin in persistent MRSA bacteraemia
Author(s) -
ChihJung Chen,
YhuChering Huang,
Cheng-Hsu Chiu
Publication year - 2015
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkv225
Subject(s) - daptomycin , glycopeptide , vancomycin , medicine , methicillin resistant staphylococcus aureus , staphylococcal infections , staphylococcus aureus , microbiology and biotechnology , bacteremia , drug resistance , antibacterial agent , antibiotics , biology , bacteria , genetics
The development of non-susceptibility to glycopeptides and daptomycin in MRSA during persistent bacteraemia has become a significant therapeutic challenge. However, the in vivo evolution and mechanism of the dual resistance have remained incompletely understood.
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