Sequencing of plasmids pAMBL1 and pAMBL2 fromPseudomonas aeruginosareveals ablaVIM-1amplification causing high-level carbapenem resistance | Zendy

Álvaro San Millán | Zendy; Macarena TollRiera | Zendy; José Antonio Escudero | Zendy; Rafael Cantón | Zendy; Teresa M. Coque | Zendy; R. Craig MacLean | Zendy

Open Access

Sequencing of plasmids pAMBL1 and pAMBL2 fromPseudomonas aeruginosareveals abla_VIM-1amplification causing high-level carbapenem resistance

Author(s) -

Álvaro San Millán,

Macarena TollRiera,

José Antonio Escudero,

Rafael Cantón,

Teresa M. Coque,

R. Craig MacLean

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv222

Subject(s) - pseudomonas aeruginosa , plasmid , microbiology and biotechnology , biology , carbapenem , pseudomonadaceae , pseudomonadales , virology , bacteria , genetics , gene , antibiotics

Carbapenemases are a major concern for the treatment of infectious diseases caused by Gram-negative bacteria. Although plasmids are responsible for the spread of resistance genes among these pathogens, there is limited information on the nature of the mobile genetic elements carrying carbapenemases in Pseudomonas aeruginosa.

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