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The mec and bla systems, among other genetic factors, are critical in regulating the expression of methicillin resistance in Staphylococcus aureus. We examined by WGS a naturally occurring oxacillin-susceptible mecA-positive S. aureus isolate to identify the mechanism conferring oxacillin susceptibility.

the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy

Whole-genome analysis of an oxacillin-susceptible CC80<i>mecA</i>-positive<i>Staphylococcus aureus</i>clinical isolate: insights into the mechanisms of cryptic methicillin resistance

Whole-genome analysis of an oxacillin-susceptible CC80mecA-positiveStaphylococcus aureusclinical isolate: insights into the mechanisms of cryptic methicillin resistance