A single nucleotide change inmutYincreases the emergence of antibiotic-resistantCampylobacter jejunimutants | Zendy

Lei Dai | Zendy; Wayne T. Muraoka | Zendy; Zuowei Wu | Zendy; Orhan Şahin | Zendy; Qijing Zhang | Zendy

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A single nucleotide change inmutYincreases the emergence of antibiotic-resistantCampylobacter jejunimutants

Author(s) -

Lei Dai,

Wayne T. Muraoka,

Zuowei Wu,

Orhan Şahin,

Qijing Zhang

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv190

Subject(s) - campylobacter jejuni , campylobacter , biology , mutant , mutation , microbiology and biotechnology , phenotype , gene , genetics , antibiotic resistance , antibiotics , point mutation , bacteria

Mutator strains play an important role in the emergence of antibiotic-resistant bacteria. Campylobacter jejuni is a leading cause of foodborne illnesses worldwide and is increasingly resistant to clinically important antibiotics. The objective of this study was to identify the genetic basis that contributes to a mutator phenotype in Campylobacter and determine the role of this phenotype in the development of antibiotic resistance.

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