High levels of macrolide resistance-associated mutations inMycoplasma genitaliumwarrant antibiotic susceptibility-guided treatment | Zendy

R.H.T. Nijhuis | Zendy; Tim T. Severs | Zendy; D. S. J. M. Van der Vegt | Zendy; Anton A. van Zwet | Zendy; Johannes G. Kusters | Zendy

Open Access

High levels of macrolide resistance-associated mutations inMycoplasma genitaliumwarrant antibiotic susceptibility-guided treatment

Author(s) -

R.H.T. Nijhuis,

Tim T. Severs,

D. S. J. M. Van der Vegt,

Anton A. van Zwet,

Johannes G. Kusters

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv136

Subject(s) - mycoplasma genitalium , 23s ribosomal rna , azithromycin , microbiology and biotechnology , moxifloxacin , biology , virology , antibiotics , chlamydia trachomatis , medicine , gene , genetics , ribosome , rna

Mycoplasma genitalium is a sexually transmitted pathogen, and infection with it is usually treated with macrolides. Unfortunately, emerging resistance to the macrolides has been associated with mutations in region V of the 23S rRNA gene. The aim of this retrospective study was to describe the incidence of macrolide resistance-associated mutations in M. genitalium from patients in the Netherlands.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research