Molecular characterization of MRSA isolates bracketing the current EUCAST ceftaroline-susceptible breakpoint forStaphylococcus aureus: the role of PBP2a in the activity of ceftaroline | Zendy

Sushmita D. Lahiri | Zendy; Robert E. McLaughlin | Zendy; James Whiteaker | Zendy; Jane E. Ambler | Zendy; Richard A. Alm | Zendy

Open Access

Molecular characterization of MRSA isolates bracketing the current EUCAST ceftaroline-susceptible breakpoint forStaphylococcus aureus: the role of PBP2a in the activity of ceftaroline

Author(s) -

Sushmita D. Lahiri,

Robert E. McLaughlin,

James Whiteaker,

Jane E. Ambler,

Richard A. Alm

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv131

Subject(s) - sccmec , staphylococcus aureus , penicillin binding proteins , microbiology and biotechnology , methicillin resistant staphylococcus aureus , biology , multilocus sequence typing , cephalosporin , penicillin , etest , population , minimum inhibitory concentration , antibiotics , medicine , genotype , bacteria , genetics , gene , environmental health

The objectives of this study were to characterize contemporary MRSA isolates and understand the prevalence and impact of sequence variability in PBP2a on ceftaroline susceptibility.

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