Time series analysis of the impact of an intervention in Tayside, Scotland to reduce primary care broad-spectrum antimicrobial use | Zendy

Virginia Hernandez Santiago | Zendy; Charis Marwick | Zendy; Andrea Patton | Zendy; Peter Davey | Zendy; Peter T. Donnan | Zendy; Bruce Guthrie | Zendy

Open Access

Time series analysis of the impact of an intervention in Tayside, Scotland to reduce primary care broad-spectrum antimicrobial use

Author(s) -

Virginia Hernandez Santiago,

Charis Marwick,

Andrea Patton,

Peter Davey,

Peter T. Donnan,

Bruce Guthrie

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv095

Subject(s) - medicine , antimicrobial , antimicrobial stewardship , interrupted time series analysis , nitrofurantoin , antibiotic resistance , psychological intervention , interrupted time series , intensive care medicine , antibiotics , nursing , chemistry , statistics , mathematics , organic chemistry , microbiology and biotechnology , biology

Concern about Clostridium difficile infection (CDI) and resistance has driven interventions internationally to reduce broad-spectrum antimicrobial use. An intervention combining guidelines, education and feedback was implemented in Tayside, Scotland in 2009 aiming to reduce primary care prescribing of co-amoxiclav, cephalosporins, fluoroquinolones and clindamycin ('4C antimicrobials'). Our aim was to assess the impact of this real-world intervention on antimicrobial prescribing rates.

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