Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission | Zendy

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Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission

Author(s) -

Antoine Chéret,

Charline Bacchus-Souffan,

Véronique Avettand-Fènoël,

Adeline Mélard,

Georges Nembot,

Catherine Blanc,

Assia Samri,

Asier SáezCirión,

Laurent Hocqueloux,

Caroline LascouxCombe,

Clotilde Allavena,

Cécile Goujard,

Marc Antoine Valantin,

A. Leplatois,

Laurence Meyer,

Christine Rouzioux,

Brigitte Autran,

Bruno Hoën,

Christophe Bourdeaux,

JeanFrançois Delfraissy,

I. Amri,

Erwan Fourn,

Yann Quertainmont,

M.Leonard Mole,

A. Rami,

A. Durel,

Myriam Diemer,

Maguy Parrinello,

Thierry Allègre,

Alain Lafeuillade,

Gilles Hittinger,

Véronique Lambry,

M. Carrerre,

G. Stevenson Philip,

Claudine Duvivier,

PaulHenri Consigny,

Caroline Charlier,

Maryam Shoai,

F. Touam,

G. Pialoux,

Laurence Slama,

Thomas L’Yavanc,

Philippe Mathurin,

Asma Adda,

V Berrebi,

Dominique Salmon,

E. Chakvetadze,

T. Tassadit,

E. Ousseima,

M.P. Pietri,

Yaniv Levy,

Anne Sophie Lascaux,

JeanDaniel Lelièvre,

M. Giovanna,

S. Dominguez,

Clément Dumont,

Christine Katlama,

M. A. Valentin,

Sophie Seang,

Lars Schneider,

N. Kiorza,

Aziza Chermak,

Saoussen Ben Abdallah,

Anne Simon,

F. Pichon,

Michèle Pauchard,

JeanMichel Molina,

C. Lascoux,

Diane Ponscarme,

Nathalie Verdière,

Anne Scemla,

N. De Castro,

A. Rachline,

Valérie Garrait,

W. Rozenbaum,

Samuel Ferret,

Suna Balkan,

F Clavel,

Mathieu Tourdjman,

Matthieu Lafaurie,

Alexandre Aslan,

Jérôme Goguel,

S. Thierry,

Victoire de Lastours,

S. Gallien,

J. Pavie,

Jonathan Delgado,

C. Mededji,

R. Verón,

Sylvie Abel,

S. Pierre-François,

C. Baringhton,

J.M. Chennebault,

Yves-Marie Vandamme,

P Fialaire,

Sami Rehaiem,

V. Rabier,

P. Abgueguen,

P. Morlat,

M.A. Vandenhende,

Noëlle Bernard,

D. Lacoste,

C. Michaux,

F. Paccalin,

M. C. Receveur,

S. Caldato,

J. Delaune,

J. M. Ragnaud,

D. Neau,

L. Lacaze-Buzy,

J. M. Livrozet,

François Jeanblanc,

Djamila Makhloufi,

F. Brunel Dalmas,

Jean-Pierre Jourdain,

Pierre Chiarello,

P. Yéni,

Bao-Chau Phung,

C. Rioux,

C. Godard,

F Louni,

Neila Talbi,

Glenn Catalano,

F. Guiroy,

J. Reynes,

JeanMarc Jacquet,

V. Fauchere,

Corinne Merle,

V. Lemoine,

M. Loriette,

David Morquin,

Alain Makinson,

N. Atoui,

Christine Tramoni,

François Raffi,

Benjamin Bonnet,

S. Bouchez,

Nicolas Feuillebois,

C. BrunetFrançois,

V. Reliquet,

O. Mounoury,

P. Morineau-Le-Houssine,

E. Billaud,

D. Brosseau,

H Hüe,

P. Dellamonica,

Michael Vassallo,

J Durant,

A. Naqvi,

A. Joulié,

Faouzi Souala,

Claude Michelet,

C. Arvieux,

P. Tattevin,

Hélène Leroy,

Matthieu Revest,

Fabien Fily,

J.-M. Chapplain,

C. M. Ratajczak,

Gabriel Gras,

L. Bernard,

J. F. Dailloux,

V. Laplantine,

L. Cuzin,

B. Marchou,

S. Larrigue,

Marie Chauveau,

Florence Balsarin,

Martine Obadia,

S. Bonne,

T. Huleux,

F. Ajana,

I. Alcaraz,

V. Baclet,

H. Melliez,

N. Viget,

X. de la Tribonnière,

E. Aissi,

Julien Poissy,

Isabelle Ravaux,

Amanda Vallon,

M. Varan,

T. May,

L. Letranchant,

C. Burty,

A. Briaud,

S. Wassoumbou,

M. Stenzel,

M P Bouillon,

Yasmine Debab,

F. Caron,

I. Gueït,

C. Chapuzet,

Franck Lebas,

Manuel Etienne,

Patrick Miailhes,

T. Perpoint,

A. Sénéchal,

I. Schlienger,

L Cotte,

C Normand,

A. Boibieux,

Tristan Ferry,

Nadia Corsini,

E. Braun,

J. Lippran,

F Biron,

C. Chidiac,

Sophie Pailhes,

Jeffrey Lipman,

J. Koffi,

V. Thoirain,

Céline BrochierArmanet,

A. Greder Belan,

A. Therby,

Sylvie Monnier,

M. Ruquet,

L. Richier,

François Prevoteau du Clary,

Patrick Philibert,

C. Chapus,

André Cabie

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv084

Subject(s) - viral replication , immunology , viral load , human immunodeficiency virus (hiv) , cd4 t cell , cell , medicine , t cell , biology , immune system , virus , genetics

Therapeutic control of HIV replication reduces the size of the viral reservoir, particularly among central memory CD4+ T cells, and this effect might be accentuated by early treatment.

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