A novel small-molecule inhibitor of hepatitis C virus replication acts by suppressing signal transducer and activator of transcription 3
Author(s) -
Yuqiang Niu,
Youhui Si,
Yan Li,
Xiaojing Chi,
Xiang Li,
Xiuying Liu,
Li Duan,
Min Cheng,
Jingjing Fan,
Shuyi Si,
Wei Yang
Publication year - 2015
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkv077
Subject(s) - hepatitis c virus , biology , stat3 , virology , replicon , viral replication , cell culture , small molecule , gene knockdown , stat protein , high throughput screening , virus , microbiology and biotechnology , gene , signal transduction , bioinformatics , biochemistry , genetics , plasmid
Hepatitis C virus (HCV) infects hepatocytes and causes liver damage. The aim of this study was to identify new classes of host-targeting anti-HCV compounds that may provide novel approaches for antiviral treatment regimens.
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