HIV-1 integrase genotyping is reliable and reproducible for routine clinical detection of integrase resistance mutations even in patients with low-level viraemia | Zendy

Daniele Armenia | Zendy; Lavinia Fabeni | Zendy; Claudia Alteri | Zendy; Domenico Di Pinto | Zendy; Domenico Di Carlo | Zendy; Ada Bertoli | Zendy; Caterina Gori | Zendy; Stefania Carta | Zendy; Valentina Fedele | Zendy; Federica Forbici | Zendy; Roberta D’Arrigo | Zendy; Valentina Svicher | Zendy; Giulia Berno | Zendy; Daniele Pizzi | Zendy; Emanuele Nicastri | Zendy; Loredana Sarmati | Zendy; Carmela Pinnetti | Zendy; Adriana Ammassari | Zendy; G. D’Offizi | Zendy; Alessandra Latini | Zendy; Massimo Andreoni | Zendy; Andrea Antinori | Zendy; Francesca CeccheriniSilberstein | Zendy; Carlo Federico Perno | Zendy; Maria Mercedes Santoro | Zendy

Open Access

HIV-1 integrase genotyping is reliable and reproducible for routine clinical detection of integrase resistance mutations even in patients with low-level viraemia

Author(s) -

Daniele Armenia,

Lavinia Fabeni,

Claudia Alteri,

Domenico Di Pinto,

Domenico Di Carlo,

Ada Bertoli,

Caterina Gori,

Stefania Carta,

Valentina Fedele,

Federica Forbici,

Roberta D’Arrigo,

Valentina Svicher,

Giulia Berno,

Daniele Pizzi,

Emanuele Nicastri,

Loredana Sarmati,

Carmela Pinnetti,

Adriana Ammassari,

G. D’Offizi,

Alessandra Latini,

Massimo Andreoni,

Andrea Antinori,

Francesca CeccheriniSilberstein,

Carlo Federico Perno,

Maria Mercedes Santoro

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkv029

Subject(s) - integrase , genotyping , integrase inhibitor , virology , human immunodeficiency virus (hiv) , lentivirus , medicine , drug resistance , biology , antiretroviral therapy , genotype , genetics , viral load , viral disease , gene

Integrase drug resistance monitoring deserves attention because of the increasing number of patients being treated with integrase strand-transfer inhibitors. Therefore, we evaluated the integrase genotyping success rate at low-level viraemia (LLV, 51-1000 copies/mL) and resistance in raltegravir-failing patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research