Antiviral activity and CSF concentrations of 600/100 mg of darunavir/ritonavir once daily in HIV-1 patients with plasma viral suppression | Zendy

María Silvana Di Yacovo | Zendy; José Moltó | Zendy; Elena Ferrer | Zendy; Adrián Curran | Zendy; Laura Else | Zendy; Magnus Gisslén | Zendy; Bonaventura Clotet | Zendy; Juan Tiraboschi | Zendy; Jordí Niubó | Zendy; Antonia Vila | Zendy; Henrik Zetterberg | Zendy; David Back | Zendy; Daniel Podzamczer | Zendy

Open Access

Antiviral activity and CSF concentrations of 600/100 mg of darunavir/ritonavir once daily in HIV-1 patients with plasma viral suppression

Author(s) -

María Silvana Di Yacovo,

José Moltó,

Elena Ferrer,

Adrián Curran,

Laura Else,

Magnus Gisslén,

Bonaventura Clotet,

Juan Tiraboschi,

Jordí Niubó,

Antonia Vila,

Henrik Zetterberg,

David Back,

Daniel Podzamczer

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku558

Subject(s) - darunavir , ritonavir , medicine , virology , human immunodeficiency virus (hiv) , lentivirus , viral load , enfuvirtide , pharmacology , viral disease , antiretroviral therapy , immunology , gp41 , antigen , epitope

The objective of this study was to assess whether a lower dose than the currently used one of darunavir/ritonavir might achieve good CSF concentrations and contribute to inhibition of CNS viral replication.

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