Dynamics of MDR Enterobacter cloacae outbreaks in a neonatal unit in Nepal: insights using wider sampling frames and next-generation sequencing | Zendy

Nicole Stoesser | Zendy; Anna E. Sheppard | Zendy; Mila Shakya | Zendy; B. R. Sthapit | Zendy; Stephen Thorson | Zendy; Adam Giess | Zendy; Dominic F. Kelly | Zendy; Andrew J. Pollard | Zendy; Tim Peto | Zendy; A. Sarah Walker | Zendy; Derrick W. Crook | Zendy

Open Access

Dynamics of MDR Enterobacter cloacae outbreaks in a neonatal unit in Nepal: insights using wider sampling frames and next-generation sequencing

Author(s) -

Nicole Stoesser,

Anna E. Sheppard,

Mila Shakya,

B. R. Sthapit,

Stephen Thorson,

Adam Giess,

Dominic F. Kelly,

Andrew J. Pollard,

Tim Peto,

A. Sarah Walker,

Derrick W. Crook

Publication year - 2015

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dku521

Subject(s) - outbreak , enterobacter cloacae , biology , microbiology and biotechnology , context (archaeology) , molecular epidemiology , virology , enterobacteriaceae , genotype , genetics , gene , escherichia coli , paleontology

There are limited data on Enterobacter cloacae outbreaks and fewer describing these in association with NDM-1. With whole-genome sequencing, we tested the hypothesis that a cluster of 16 E. cloacae bacteraemia cases in a Nepali neonatal unit represented a single clonal outbreak, using a wider set of epidemiologically unrelated clinical E. cloacae isolates for comparison.

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