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Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against β-lactam antibiotics
Author(s) -
Régis Stentz,
Nikki Horn,
Kathryn Cross,
Louise J. Salt,
Charles A. Brearley,
David M. Livermore,
Simon R. Carding
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku466
Subject(s) - bacteroides thetaiotaomicron , microbiology and biotechnology , cefotaxime , bacteroides fragilis , bacterial outer membrane , bacteroides , biology , salmonella , pseudomonas aeruginosa , bacteria , antibiotics , gene , escherichia coli , genetics
To identify β-lactamase genes in gut commensal Bacteroides species and to assess the impact of these enzymes, when carried by outer membrane vesicles (OMVs), in protecting enteric pathogens and commensals.

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