In vivo Candida glabrata biofilm development on foreign bodies in a rat subcutaneous model
Author(s) -
Soňa Kucharíková,
Bram Neirinck,
Nidhi Sharma,
Jef Vleugels,
Katrien Lagrou,
Patrick Van Dijck
Publication year - 2014
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dku447
Subject(s) - candida glabrata , in vivo , biofilm , microbiology and biotechnology , medicine , bacteria , candida albicans , biology , genetics
Biofilm studies have been mostly dedicated to the major human fungal pathogen Candida albicans, whereas much less is known about this virulence factor in Candida glabrata, certainly under in vivo conditions. This study provides a deeper understanding of the biofilm development of C. glabrata, its architecture and susceptibility profile to fluconazole and echinocandins.
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